GPB cream reduces excessive underarm sweating

British Journal of DermatologyVolume 185, Issue 2 p. e40-e40 Plain Language SummaryFree Access GPB cream reduces excessive underarm sweating First published: 16 August 2021 https://doi.org/10.1111/bjd.20532AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text full-text accessPlease review our Terms and Conditions Use check box below share version article.I have read accept the Wiley Online Library UseShareable LinkUse link a this article with your friends colleagues. Learn more.Copy URL Share linkShare onFacebookTwitterLinked InRedditWechat Abstract Linked Article: Abels et al. Br J Dermatol 2021; 185:315–322. Approximately 5% people worldwide suffer from permanent sweating, so-called ‘primary hyperhidrosis’, which has severe impact on their quality life. Yet, more than 50% all hyperhidrosis receive no treatment. Patients primary axillary an amount sweat production in armpits beyond what is needed order regulate normal body temperature. In clinical trial, conducted Germany, Hungary, Sweden, Denmark UK, 171 patients condition applied either containing 1% glycopyrronium bromide (GPB) or without (a placebo, looked like being tested but that did not contain any medicine) every day for 4 weeks. Reduction total (measured by weighing absorbed over 5-minute period) was statistically significantly higher compared placebo cream. improved patient’s Only mild moderate side-effects were reported patients; most one dry mouth. The irritate skin armpits. This study provides further evidence effective treatment formulation beneficial terms local tolerability overall safety. long-term safety effectiveness part trial (over period 72 weeks) currently underway. These data will be another step towards approval various European Union countries. conclusion, may provide new option sweating. Volume185, Issue2August 2021Pages RelatedInformation